The answer may depend on the type of pictures and the intended purpose
of the document.
You may wish to conduct a few experiments, making sure to compare
actual doc sizes and actual output quality in the intended output
types.
IE: how does it print on whatever it will need to be printed on?
Does it still PDF ok, if that is needed?
Does the PDF view ok? does the PDF print ok? in B&W? in color?
etc..